A master’s thesis in the Department of Life Sciences, College of Science – University of Kerbala, presented by Iman Faleh Hadi, investigated the relationship between type 2 diabetes and the progression of non-alcoholic fatty liver disease (NAFLD) through the analysis of various physiological and biochemical parameters.

The study found elevated ALT enzyme levels in diabetic patients compared to healthy individuals and confirmed the association between insulin resistance and NAFLD progression. Additionally, it highlighted the potential use of adiponectin and asprosin as non-invasive biomarkers for detecting fatty liver disease, with adiponectin outperforming insulin in distinguishing between patients and healthy individuals.

The study recommended regular liver enzyme tests and ultrasound screenings, particularly for individuals over 50 years old or those with metabolic syndrome. It also suggested using APRI and FIB-4 scores as non-invasive methods for disease assessment.